6ZPL: Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor, sybody Sb_GlyT1#7 and bound Na and Cl ions

PDB ID: 6ZPLDownload
MMDB ID: 199856
PDB Deposition Date: 2020/7/8
Updated in MMDB: 2021/03
Experimental Method:
x-ray diffraction
Resolution: 3.945  Å
Source Organism:
Acetivibrio thermocellus ATCC 27405▼
Similar Structures:
Biological Unit for 6ZPL: pentameric; determined by author
Molecular Components in 6ZPL
Label Count Molecule
Proteins (5 molecules)
2
Sodium- and Chloride-dependent Glycine Transporter 1
Molecule annotation
1
Endoglucanase H
Molecule annotation
2
Sybody Sb_glyt1#7
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
[5-fluoranyl-6-(oxan-4-yloxy)-1,3-dihydroisoindol-2-yl]-[5-methylsulfonyl-2-[2,2,3,3,3-pentakis(fluoranyl)propoxy]phenyl]methanone[5-fluoranyl-6-(oxan-4-yloxy)-1,3-dihydroisoindol-2-yl]-[5-methylsulfonyl-2-[2,2,3,3,3-pentakis(fluoranyl)propoxy]phenyl]methanone
2
2
SODIUM IONSODIUM ION
3
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303