6ZOH: 3-Formylrifamycin SV binding to the access pocket of AcrB-G619P_G621P L and T protomers

PDB ID: 6ZOHDownload
MMDB ID: 202043
PDB Deposition Date: 2020/7/7
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Escherichia coli K-12▼
Similar Structures:
Biological Unit for 6ZOH: pentameric; determined by author and by software (PISA)
Molecular Components in 6ZOH
Label Count Molecule
Proteins (5 molecules)
3
Multidrug Efflux Pump Subunit Acrb
Molecule annotation
2
Darpin
Molecule annotation
Chemicals and Non-standard biopolymers (35 molecules)
1
7
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
2
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
4
GLYCEROLGLYCEROL
4
4
DODECANEDODECANE
5
2
DECYLAMINE-N,N-DIMETHYL-N-OXIDEDECYLAMINE-N,N-DIMETHYL-N-OXIDE
6
2
(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-8-formyl-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptam ethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate(2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-8-formyl-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptam ethyl-1,11-dioxo-1,2-dihydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate
7
1
(2S)-3-hydroxypropane-1,2-diyl didecanoate(2S)-3-hydroxypropane-1,2-diyl didecanoate
8
1
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
9
1
DECANEDECANE
10
1
(2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate(2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate
11
2
HEXANEHEXANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303