6ZO5: Fusidic acid binding to the TM1/TM2 groove of AcrB-G619P_G621P

PDB ID: 6ZO5Download
MMDB ID: 202031
PDB Deposition Date: 2020/7/7
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Escherichia coli K-12▼
Similar Structures:
Biological Unit for 6ZO5: pentameric; determined by author and by software (PISA)
Molecular Components in 6ZO5
Label Count Molecule
Proteins (5 molecules)
3
Multidrug Efflux Pump Subunit Acrb
Molecule annotation
2
Darpin
Molecule annotation
Chemicals and Non-standard biopolymers (54 molecules)
1
1
3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL
2
8
DODECYL-BETA-D-MALTOSIDEDODECYL-BETA-D-MALTOSIDE
3
4
DODECANEDODECANE
4
5
DECANEDECANE
5
8
GLYCEROLGLYCEROL
6
7
HEXANEHEXANE
7
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
8
1
(2S)-3-hydroxypropane-1,2-diyl didecanoate(2S)-3-hydroxypropane-1,2-diyl didecanoate
9
1
FUSIDIC ACIDFUSIDIC ACID
10
3
TETRADECANETETRADECANE
11
3
SULFATE IONSULFATE ION
12
2
(2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate(2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate
13
2
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
14
1
PHOSPHATIDYLETHANOLAMINEPHOSPHATIDYLETHANOLAMINE
15
1
N-OCTANEN-OCTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303