6ZND: [1,2,4]Triazolo[1,5-a]pyrimidine Phosphodiesterase 2 Inhibitors

PDB ID: 6ZNDDownload
MMDB ID: 190514
PDB Deposition Date: 2020/7/6
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZND: monomeric; determined by author
Molecular Components in 6ZND
Label Count Molecule
Protein (1 molecule)
1
Cgmp-dependent 3',5'-cyclic Phosphodiesterase
(Gene symbol: PDE2A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
[(3~{S})-3-([1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-(3,4,5-trimethoxyphenyl)methanone[(3~{S})-3-([1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303