6ZGC: Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound Saracatinib (AZD0530)

PDB ID: 6ZGCDownload
MMDB ID: 190697
PDB Deposition Date: 2020/6/18
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.67  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZGC: monomeric; determined by author
Molecular Components in 6ZGC
Label Count Molecule
Protein (1 molecule)
1
Activin Receptor Type I
(Gene symbol: ACVR1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
N-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINEN-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-7-[2-(4-METHYLPIPERAZIN-1-YL)ETHOXY]-5-(TETRAHYDRO-2H-PYRAN-4-YLOXY)QUINAZOLIN-4-AMINE
2
4
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303