6ZEY: Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction

PDB ID: 6ZEYDownload
MMDB ID: 200893
PDB Deposition Date: 2020/6/16
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 1.801  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZEY: monomeric; determined by author and by software (PISA)
Molecular Components in 6ZEY
Label Count Molecule
Protein (1 molecule)
1
Kelch-like Ech-associated Protein 1
(Gene symbol: Keap1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
5
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
1
5-cyclopropyl-1-[3-(phenylsulfonylamino)phenyl]pyrazole-4-carboxylic acid5-cyclopropyl-1-[3-(phenylsulfonylamino)phenyl]pyrazole-4-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303