6ZED: CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX with compound F1

PDB ID: 6ZEDDownload
MMDB ID: 193020
PDB Deposition Date: 2020/6/16
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 1.08  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZED: monomeric; determined by author and by software (PISA)
Molecular Components in 6ZED
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4,5-dimethyl-1~{H}-pyrazolo[3,4-c]pyridazin-3-amine4,5-dimethyl-1~{H}-pyrazolo[3,4-c]pyridazin-3-amine
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303