6ZCY: SYK Kinase domain in complex with diamine inhibitor 16

PDB ID: 6ZCYDownload
MMDB ID: 203356
PDB Deposition Date: 2020/6/12
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.81  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZCY: monomeric; determined by author and by software (PISA)
Molecular Components in 6ZCY
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase SYK
(Gene symbol: SYK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{R})-pyrrolidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide~{N},1-dimethyl-5-[[4-[3-methyl-4-[[(3~{R})-pyrrolidin-3-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]indazole-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303