6ZCI: Crystal structure of BRD4-BD1 in complex with NVS-BET-1

PDB ID: 6ZCIDownload
MMDB ID: 196789
PDB Deposition Date: 2020/6/11
Updated in MMDB: 2021/03
Experimental Method:
x-ray diffraction
Resolution: 1.976  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZCI: monomeric; determined by author
Molecular Components in 6ZCI
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4~{R})-4-(4-chlorophenyl)-1-cyclopropyl-5-(1,5-dimethyl-6-oxidanylidene-pyridin-3-yl)-3-methyl-4~{H}-pyrrolo[3,4-c]pyrazol-6-one(4~{R})-4-(4-chlorophenyl)-1-cyclopropyl-5-(1,5-dimethyl-6-oxidanylidene-pyridin-3-yl)-3-methyl-4~{H}-pyrrolo[3,4-c]pyrazol-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303