6ZC8: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling

PDB ID: 6ZC8Download
MMDB ID: 203348
PDB Deposition Date: 2020/6/10
Updated in MMDB: 2022/07
Experimental Method:
x-ray diffraction
Resolution: 2.76  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZC8: monomeric; determined by author
Molecular Components in 6ZC8
Label Count Molecule
Protein (1 molecule)
1
Segment Polarity Protein Dishevelled Homolog Dvl-3
(Gene symbol: DVL3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[[3-chloranyl-4-[(1~{H}-indazol-3-ylcarbonylamino)methyl]phenyl]sulfonylamino]-5-methyl-benzoic acid2-[[3-chloranyl-4-[(1~{H}-indazol-3-ylcarbonylamino)methyl]phenyl]sulfonylamino]-5-methyl-benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303