6ZC7: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling

PDB ID: 6ZC7Download
MMDB ID: 203347
PDB Deposition Date: 2020/6/9
Updated in MMDB: 2022/07
Experimental Method:
x-ray diffraction
Resolution: 1.48  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZC7: monomeric; determined by author
Molecular Components in 6ZC7
Label Count Molecule
Protein (1 molecule)
1
Dishevelled, DSH Homolog 3 (Drosophila), Isoform Cra_b
(Gene symbol: DVL3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
5-bromanyl-2-[(phenylmethyl)sulfonylamino]benzoic acid5-bromanyl-2-[(phenylmethyl)sulfonylamino]benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303