6ZC3: Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling

PDB ID: 6ZC3Download
MMDB ID: 203344
PDB Deposition Date: 2020/6/9
Updated in MMDB: 2022/07
Experimental Method:
x-ray diffraction
Resolution: 1.67  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZC3: monomeric; determined by author
Molecular Components in 6ZC3
Label Count Molecule
Protein (1 molecule)
1
Dishevelled, DSH Homolog 3 (Drosophila), Isoform Cra_b
(Gene symbol: DVL3)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
5-fluoranyl-2-(methylsulfonylamino)benzoic acid5-fluoranyl-2-(methylsulfonylamino)benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303