6ZC0: SYK Kinase domain in complex with azabenzimidazole inhibitor 2b

PDB ID: 6ZC0Download
MMDB ID: 203343
PDB Deposition Date: 2020/6/9
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.97  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZC0: monomeric; determined by author
Molecular Components in 6ZC0
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase SYK
(Gene symbol: SYK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N},~{N}-dimethyl-1-[1-[2-(1-methylindol-4-yl)-3~{H}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]methanamine~{N},~{N}-dimethyl-1-[1-[2-(1-methylindol-4-yl)-3~{H}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]methanamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303