6ZA8: Crystal structure of the neurotensin receptor 1 in complex with the small-molecule partial agonist RTI-3a

PDB ID: 6ZA8Download
MMDB ID: 198577
PDB Deposition Date: 2020/6/5
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.72  Å
Source Organism:
Similar Structures:
Biological Unit for 6ZA8: monomeric; determined by author and by software (PISA)
Molecular Components in 6ZA8
Label Count Molecule
Protein (1 molecule)
1
Neurotensin Receptor Type 1,neurotensin Receptor Type 1,neurotensin Receptor 1 (Ntsr1),neurotensin Receptor 1 (Ntsr1),neurotensin Receptor Type 1,neurotensin Receptor 1 (Ntsr1),neurotensin Receptor 1 (Ntsr1)
(Gene symbol: Ntsr1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2~{S})-2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]-4-methyl-pentanoic acid(2~{S})-2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]-4-methyl-pentanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303