6Z7L: N-TERMINAL BROMODOMAIN OF HUMAN BRD4 with GSK789

PDB ID: 6Z7LDownload
MMDB ID: 193011
PDB Deposition Date: 2020/5/31
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 1.624  Å
Source Organism:
Similar Structures:
Biological Unit for 6Z7L: monomeric; determined by author and by software (PISA)
Molecular Components in 6Z7L
Label Count Molecule
Protein (1 molecule)
1
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3~{R},4~{R})-~{N}-cyclohexyl-4-[[5-(furan-2-yl)-3-methyl-2-oxidanylidene-1~{H}-1,7-naphthyridin-8-yl]amino]-1-methyl-piperidine-3-carboxamide(3~{R},4~{R})-~{N}-cyclohexyl-4-[[5-(furan-2-yl)-3-methyl-2-oxidanylidene-1~{H}-1,7-naphthyridin-8-yl]amino]-1-methyl-piperidine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303