6Z5E: Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004093

PDB ID: 6Z5EDownload
MMDB ID: 188552
PDB Deposition Date: 2020/5/26
Updated in MMDB: 2020/06
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6Z5E: monomeric; determined by author and by software (PISA)
Molecular Components in 6Z5E
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Kinase Haspin
(Gene symbol: HASPIN)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
2
SODIUM IONSODIUM ION
3
1
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
4
1
SUCCINIC ACIDSUCCINIC ACID
5
1
11-cyclopropyl-14-(2-hydroxyethyl)-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one11-cyclopropyl-14-(2-hydroxyethyl)-8,11,14,18,19,22-hexazatetracyclo[13.5.2.12,6.018,21]tricosa-1(21),2(23),3,5,15(22),16,19-heptaen-7-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303