6Z4Y: Crystal structure of Aurora A (STK6) in complex with macrocycle ODS2003208

PDB ID: 6Z4YDownload
MMDB ID: 188536
PDB Deposition Date: 2020/5/26
Updated in MMDB: 2020/06
Experimental Method:
x-ray diffraction
Resolution: 2.25  Å
Source Organism:
Similar Structures:
Biological Unit for 6Z4Y: monomeric; determined by author and by software (PISA)
Molecular Components in 6Z4Y
Label Count Molecule
Protein (1 molecule)
1
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
CITRIC ACIDCITRIC ACID
2
5
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one6-(2-methoxyethoxy)-11-methyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303