6Z4S: Crystal structure of the neurotensin receptor 1 (NTSR1-H4bmx) in complex with the small molecule inverse agonist SR48692

PDB ID: 6Z4SDownload
MMDB ID: 198571
PDB Deposition Date: 2020/5/25
Updated in MMDB: 2021/02
Experimental Method:
x-ray diffraction
Resolution: 2.707  Å
Source Organism:
Similar Structures:
Biological Unit for 6Z4S: monomeric; determined by author and by software (PISA)
Molecular Components in 6Z4S
Label Count Molecule
Protein (1 molecule)
1
Neurotensin Receptor Type 1,darpin,hrv 3C Protease Recognition Sequence
(Gene symbol: Ntsr1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303