6Z45: CDK9-Cyclin-T1 complex bound by compound 24

PDB ID: 6Z45Download
MMDB ID: 196788
PDB Deposition Date: 2020/5/22
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 3.37  Å
Source Organism:
Similar Structures:
Biological Unit for 6Z45: dimeric; determined by author and by software (PISA)
Molecular Components in 6Z45
Label Count Molecule
Proteins (2 molecules)
1
Cyclin-dependent Kinase 9
(Gene symbol: CDK9)
Molecule annotation
1
Cyclin-t1
(Gene symbol: CCNT1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(1~{S},3~{R})-3-acetamido-~{N}-[5-chloranyl-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide(1~{S},3~{R})-3-acetamido-~{N}-[5-chloranyl-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide
2
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
3
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303