6YYO: Structure of Cathepsin S in complex with Compound 1

PDB ID: 6YYODownload
MMDB ID: 201855
PDB Deposition Date: 2020/5/5
Updated in MMDB: 2022/11
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6YYO: dimeric; determined by author and by software (PISA)
Molecular Components in 6YYO
Label Count Molecule
Proteins (2 molecules)
2
Cathepsin S
(Gene symbol: CTSS)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
4
SULFATE IONSULFATE ION
2
32
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
6-(4-methylsulfonylpiperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine6-(4-methylsulfonylpiperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine
5
1
CITRATE ANIONCITRATE ANION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303