6YYG: Crystal Structure of 5-(trifluoromethoxy)indoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C

PDB ID: 6YYGDownload
MMDB ID: 201852
PDB Deposition Date: 2020/5/5
Updated in MMDB: 2021/05
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 6YYG: monomeric; determined by author
Molecular Components in 6YYG
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase BTK
(Gene symbol: BTK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
5-(trifluoromethyloxy)-1,3-dihydroindol-2-one5-(trifluoromethyloxy)-1,3-dihydroindol-2-one
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303