6YXI: Structure of Notum in complex with a 1-(3-Chlorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid inhibitor

PDB ID: 6YXIDownload
MMDB ID: 191496
PDB Deposition Date: 2020/5/1
Updated in MMDB: 2020/09
Experimental Method:
x-ray diffraction
Resolution: 1.34  Å
Source Organism:
Similar Structures:
Biological Unit for 6YXI: monomeric; determined by author
Molecular Components in 6YXI
Label Count Molecule
Protein (1 molecule)
1
Palmitoleoyl-protein Carboxylesterase Notum
(Gene symbol: NOTUM)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
1-(3-chlorophenyl)-2,5-dimethyl-pyrrole-3-carboxylic acid1-(3-chlorophenyl)-2,5-dimethyl-pyrrole-3-carboxylic acid
2
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
7
SULFATE IONSULFATE ION
5
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303