6YVZ: HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic JLS-367

PDB ID: 6YVZDownload
MMDB ID: 196984
PDB Deposition Date: 2020/4/29
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 1.91  Å
Source Organism:
Similar Structures:
Biological Unit for 6YVZ: monomeric; determined by author and by software (PISA)
Molecular Components in 6YVZ
Label Count Molecule
Protein (1 molecule)
1
EGL Nine Homolog 1
(Gene symbol: EGLN1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
MANGANESE (II) IONMANGANESE (II) ION
2
1
4-[(5-bromanylisoquinolin-3-yl)amino]-4-oxidanylidene-butanoic acid4-[(5-bromanylisoquinolin-3-yl)amino]-4-oxidanylidene-butanoic acid
3
1
BICARBONATE IONBICARBONATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303