6YTR: Structure of recombinant human beta-glucocerebrosidase in complex with cyclophellitol aziridine inhibitor

PDB ID: 6YTRDownload
MMDB ID: 201818
PDB Deposition Date: 2020/4/24
Updated in MMDB: 2021/12
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6YTR: monomeric; determined by author
Molecular Components in 6YTR
Label Count Molecule
Protein (1 molecule)
1
Lysosomal Acid Glucosylceramidase
(Gene symbol: GBA)
Molecule annotation
Chemicals and Non-standard biopolymers (32 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-D-mannopyranosealpha-D-mannopyranose
3
1
(1~{R},2~{S},3~{S},4~{S},5~{R},6~{R})-5-azanyl-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol(1~{R},2~{S},3~{S},4~{S},5~{R},6~{R})-5-azanyl-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
4
4
SULFATE IONSULFATE ION
5
22
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303