6YQ1: FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(3-{[2-(2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-methyl}-pyridin-2-yl)-methanesulfonamide

PDB ID: 6YQ1Download
MMDB ID: 198560
PDB Deposition Date: 2020/4/16
Updated in MMDB: 2021/06
Experimental Method:
x-ray diffraction
Resolution: 1.784  Å
Source Organism:
Similar Structures:
Biological Unit for 6YQ1: monomeric; determined by author
Molecular Components in 6YQ1
Label Count Molecule
Protein (1 molecule)
1
Focal Adhesion Kinase 1
(Gene symbol: PTK2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
~{N}-methyl-~{N}-[3-[[[2-[(2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide~{N}-methyl-~{N}-[3-[[[2-[(2-oxidanylidene-3,4-dihydro-1~{H}-quinolin-6-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide
2
1
SODIUM IONSODIUM ION
3
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303