6YPP: Crystal structure of the cAMP-dependent protein kinase A cocrystallized with PKI (5-24). Soaking of aminofasudil and displacing it with the fragment isoquinoline

PDB ID: 6YPPDownload
MMDB ID: 201347
PDB Deposition Date: 2020/4/16
Updated in MMDB: 2021/04
Experimental Method:
x-ray diffraction
Resolution: 1.75  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 6YPP: dimeric; determined by software (PISA)
Molecular Components in 6YPP
Label Count Molecule
Proteins (2 molecules)
1
Camp-dependent Protein Kinase Catalytic Subunit Alpha
Molecule annotation
1
Camp-dependent Protein Kinase Inhibitor Alpha
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ISOQUINOLINEISOQUINOLINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303