6YNB: Crystal structure of cAMP-dependent Protein Kinase (PKA) in complex with short-chain Fasudil-derivative N-(2-aminoethyl)isoquinoline-5-sulfonamide (soaked)

PDB ID: 6YNBDownload
MMDB ID: 194067
PDB Deposition Date: 2020/4/13
Updated in MMDB: 2020/10
Experimental Method:
x-ray diffraction
Resolution: 1.72  Å
Similar Structures:
Biological Unit for 6YNB: dimeric; determined by author and by software (PISA)
Molecular Components in 6YNB
Label Count Molecule
Proteins (2 molecules)
1
Camp-dependent Protein Kinase Catalytic Subunit Alpha
(Gene symbol: Prkaca)
Molecule annotation
1
Camp-dependent Protein Kinase Inhibitor Alpha
(Gene symbol: Pkia)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-(2-AMINOETHYL)ISOQUINOLINE-5-SULFONAMIDEN-(2-AMINOETHYL)ISOQUINOLINE-5-SULFONAMIDE
2
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303