6YKY: Biochemical, Cellular and Structural Characterization of Novel ERK3 Inhibitors

PDB ID: 6YKYDownload
MMDB ID: 193181
PDB Deposition Date: 2020/4/6
Updated in MMDB: 2020/10
Experimental Method:
x-ray diffraction
Resolution: 2.52  Å
Source Organism:
Similar Structures:
Biological Unit for 6YKY: monomeric; determined by author
Molecular Components in 6YKY
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 6
(Gene symbol: MAPK6)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
3-(4-methoxyphenyl)-~{N}-[(3~{R})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine3-(4-methoxyphenyl)-~{N}-[(3~{R})-1-pyridin-4-ylpyrrolidin-3-yl]-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303