6YI6: Structural and Kinetic Evaluation of Phosphoramidate Inhibitors on Thermolysin

PDB ID: 6YI6Download
MMDB ID: 200851
PDB Deposition Date: 2020/4/1
Updated in MMDB: 2021/04
Experimental Method:
x-ray diffraction
Resolution: 1.44  Å
Source Organism:
Similar Structures:
Biological Unit for 6YI6: monomeric; determined by author and by software (PISA)
Molecular Components in 6YI6
Label Count Molecule
Protein (1 molecule)
1
Thermolysin
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
ZINC IONZINC ION
2
4
CALCIUM IONCALCIUM ION
3
2
CESIUM IONCESIUM ION
4
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
(2~{S})-2-[[(2~{S})-4-methyl-2-[[oxidanyl-[(1~{S})-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]amino]pentanoyl]amino]propanoic acid(2~{S})-2-[[(2~{S})-4-methyl-2-[[oxidanyl-[(1~{S})-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]amino]pentanoyl]amino]propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303