6YG7: Crystal structure of MKK7 (MAP2K7) covalently bound with type-II inhibitor SB1-G-23

PDB ID: 6YG7Download
MMDB ID: 191228
PDB Deposition Date: 2020/3/27
Updated in MMDB: 2020/09
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6YG7: dimeric; determined by author
Molecular Components in 6YG7
Label Count Molecule
Proteins (2 molecules)
2
Dual Specificity Mitogen-activated Protein Kinase Kinase 7
(Gene symbol: MAP2K7)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
~{N}-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-[[(3~{R})-1-propanoylpyrrolidin-3-yl]amino]pyrimidin-4-yl]oxy-benzamide~{N}-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[2-[[(3~{R})-1-propanoylpyrrolidin-3-yl]amino]pyrimidin-4-yl]oxy-benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303