6YE1: Human Ecto-5'-nucleotidase (CD73) in complex with the AMPCP derivative A894 (compound 2n in publication) in the closed form (crystal form IV)

PDB ID: 6YE1Download
MMDB ID: 197685
PDB Deposition Date: 2020/3/23
Updated in MMDB: 2024/01
Experimental Method:
x-ray diffraction
Resolution: 2.66  Å
Source Organism:
Similar Structures:
Biological Unit for 6YE1: dimeric; determined by author and by software (PISA)
Molecular Components in 6YE1
Label Count Molecule
Proteins (2 molecules)
2
5'-nucleotidase
(Gene symbol: NT5E)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
ZINC IONZINC ION
2
2
[(2~{R},3~{S},4~{R},5~{R})-5-[2-chloranyl-6-(cyclopentylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxymethylphosphonic acid[(2~{R},3~{S},4~{R},5~{R})-5-[2-chloranyl-6-(cyclopentylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxymethylphosphonic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303