6YD4: X-ray structure of furin in complex with the canavanine-based inhibitor 4-guanidinomethyl-phenylacetyl-Canavanine-Tle-Canavanine-Amba

PDB ID: 6YD4Download
MMDB ID: 198834
PDB Deposition Date: 2020/3/20
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 6YD4: dimeric; determined by author and by software (PISA)
Molecular Components in 6YD4
Label Count Molecule
Protein (1 molecule)
1
Furin
(Gene symbol: FURIN)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
B
1
4-guanidinomethyl-phenylacetyl-Canavanine-Tle-Canavanine-Amba
1
1
2-[4-(carbamimidamidomethyl)phenyl]ethanoic acid2-[4-(carbamimidamidomethyl)phenyl]ethanoic acid
2
3
CALCIUM IONCALCIUM ION
3
3
SODIUM IONSODIUM ION
4
1
CHLORIDE IONCHLORIDE ION
5
2
PHOSPHATE IONPHOSPHATE ION
6
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
7
4
Molecule information is not available.
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303