6YBK: Structure of MBP-Mcl-1 in complex with compound 4d

PDB ID: 6YBKDownload
MMDB ID: 194734
PDB Deposition Date: 2020/3/17
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6YBK: monomeric; determined by author and by software (PISA)
Molecular Components in 6YBK
Label Count Molecule
Protein (1 molecule)
1
Maltose/maltodextrin-binding Periplasmic Protein,induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
(Gene symbol: MCL1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
alpha-D-glucopyranosealpha-D-glucopyranose
2
1
CHLORIDE IONCHLORIDE ION
3
1
(2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-(pyrazin-2-ylmethoxy)phenyl]propanoic acid(2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-(pyrazin-2-ylmethoxy)phenyl]propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303