National Center for
Biotechnology Information

6YAM: Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA

PDB ID:

6YAM Download

MMDB ID:

191066

PDB Deposition Date:

2020/3/12

Updated in MMDB:

2022/11

Experimental Method:

electron microscopy

Resolution:

3.6 Å

Source Organism:

Oryctolagus cuniculus▼

Taxonomy	Molecule
Oryctolagus cuniculus	1, l, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, S, T, V, W, X, Y, Z, a, b, c, d, e, f, g, n, i, 2 , A, B, j, k, U, R, m, y, v, w, q, r, s, t, u
Homo sapiens	3

Similar Structures:

Biological Unit for 6YAM: 50-meric; determined by author

Molecular Components in 6YAM
Label	Count	Molecule
Proteins (47 molecules)
l	1	60S Ribosomal Protein L41
C	1	40S Ribosomal Protein US2
D	1	40S Ribosomal Protein ES1
E	1	40S Ribosomal Protein US5
F	1	40S Ribosomal Protein US3
G	1	40S Ribosomal Protein ES4
H	1	40S Ribosomal Protein US7
I	1	40S Ribosomal Protein ES6
J	1	Ribosomal Protein ES7
K	1	40S Ribosomal Protein ES8
L	1	40S Ribosomal Protein US4
M	1	40S Ribosomal Protein Es10
N	1	40S Ribosomal Protein Us17
O	1	40S Ribosomal Protein Es12
P	1	Ribosomal Protein Us15
Q	1	40S Ribosomal Protein Us11
S	1	40S Ribosomal Protein US9
T	1	40S Ribosomal Protein Es17
V	1	40S Ribosomal Protein Es19
W	1	40S Ribosomal Protein Us10
X	1	40S Ribosomal Protein Es21
Y	1	40S Ribosomal Protein US8
Z	1	40S Ribosomal Protein Us12
a	1	40S Ribosomal Protein Es24
b	1	40S Ribosomal Protein Es26
c	1	40S Ribosomal Protein Es27
d	1	40S Ribosomal Protein Es28
e	1	Ribosomal Protein Us14
f	1	Ribosomal Protein Es31
g	1	Ribosomal Protein Rack1
n	1	Ribosomal Protein Es25
i	1	40S Ribosomal Protein Es30
A	1	Eukaryotic Translation Initiation Factor 2 Subunit Alpha
B	1	Eukaryotic Translation Initiation Factor 2 Subunit Gamma
j	1	Eukaryotic Translation Initiation Factor 1A
k	1	Atp-binding Cassette Sub-family E Member 1 (Abce1)
U	1	40S Ribosomal Protein Us13
R	1	40S Ribosomal Protein Us19
m	1	Eukaryotic Translation Initiation Factor 3 Subunit D
y	1	Eukaryotic Translation Initiation Factor 3 Subunit a
v	1	Eukaryotic Translation Initiation Factor 3 Subunit C
w	1	Eukaryotic Translation Initiation Factor 3 Subunit E
q	1	Eukaryotic Translation Initiation Factor 3 Subunit F
r	1	Eukaryotic Translation Initiation Factor 3 Subunit H
s	1	Eukaryotic Translation Initiation Factor 3 Subunit K
t	1	Eukaryotic Translation Initiation Factor 3 Subunit L
u	1	Eukaryotic Translation Initiation Factor 3 Subunit M
Nucleotides(3 molecules)
1	1	Initiator Methionylated tRNA
2	1	18S Ribosomal RNA
3	1	Beta-globin mRNA
Chemicals and Non-standard biopolymers (5 molecules)
1	2	IRON/SULFUR CLUSTER
2	1	MAGNESIUM ION
3	2	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

* Click molecule labels to explore molecular sequence information.

Citing MMDB

Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303