6Y9S: Crystal structure of GSK-3b in complex with the imidazo[1,5-a]pyridine-3-carboxamide inhibitor 16

PDB ID: 6Y9SDownload
MMDB ID: 187870
PDB Deposition Date: 2020/3/10
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.03  Å
Source Organism:
Similar Structures:
Biological Unit for 6Y9S: monomeric; determined by author
Molecular Components in 6Y9S
Label Count Molecule
Protein (1 molecule)
1
Glycogen Synthase Kinase-3 Beta
(Gene symbol: GSK3B)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
~{N}-(oxan-4-ylmethyl)-6-(5-propan-2-yloxypyridin-3-yl)imidazo[1,5-a]pyridine-3-carboxamide~{N}-(oxan-4-ylmethyl)-6-(5-propan-2-yloxypyridin-3-yl)imidazo[1,5-a]pyridine-3-carboxamide
2
2
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303