6Y7T: Engineered conjugation of lysine-specific molecular tweezers with ExoS derived peptidic inhibitor enhance affinity towards target protein 14-3-3 through ditopic binding

PDB ID: 6Y7TDownload
MMDB ID: 200320
PDB Deposition Date: 2020/3/2
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 6Y7T: trimeric; determined by author
Molecular Components in 6Y7T
Label Count Molecule
Proteins (3 molecules)
2
14-3-3 Protein Sigma
Molecule annotation
1
Exoenzyme S
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ExoSTWZ molecular tweezerExoSTWZ molecular tweezer
2
3
SODIUM IONSODIUM ION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303