6Y5D: Structure of human cGAS (K394E) bound to the nucleosome

PDB ID: 6Y5DDownload
MMDB ID: 193177
PDB Deposition Date: 2020/2/25
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 4.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6Y5D: 22-meric; determined by author
Molecular Components in 6Y5D
Label Count Molecule
Proteins (18 molecules)
4
Histone H3.2
(Gene symbol: H3C14)
Molecule annotation
4
Histone H4
(Gene symbol: H4C9)
Molecule annotation
4
Histone H2A Type 2-A
(Gene symbol: H2AC18)
Molecule annotation
4
Histone H2B Type 1-K
(Gene symbol: H2BC12)
Molecule annotation
2
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Nucleotides(4 molecules)
2
DNA (153-mer)
Molecule annotation
2
DNA (153-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
9
PENTANEDIALPENTANEDIAL
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303