6Y4Q: Structure of a stapled peptide bound to MDM2

PDB ID: 6Y4QDownload
MMDB ID: 187866
PDB Deposition Date: 2020/2/22
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 1.63  Å
Source Organism:
Similar Structures:
Biological Unit for 6Y4Q: dimeric; determined by author and by software (PISA)
Molecular Components in 6Y4Q
Label Count Molecule
Proteins (2 molecules)
1
E3 Ubiquitin-protein Ligase Mdm2
(Gene symbol: MDM2)
Molecule annotation
1
Ace-leu-thr-phe-gly-glu-tyr-trp-ala-gln-leu-ala-ser
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-[(1-ethyl-1,2,3-triazol-4-yl)methyl]-~{N},5-dimethyl-4-[2-[2-methyl-5-[methyl-[(1-propyl-1,2,3-triazol-4-yl)methyl]carbamoyl]thiophen-3-yl]cyclopenten-1-yl]thiophene-2-carboxamide~{N}-[(1-ethyl-1,2,3-triazol-4-yl)methyl]-~{N},5-dimethyl-4-[2-[2-methyl-5-[methyl-[(1-propyl-1,2,3-triazol-4-yl)methyl]carbamoyl]thiophen-3-yl]cyclopenten-1-yl]thiophene-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303