6Y08: Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole

PDB ID: 6Y08Download
MMDB ID: 198804
PDB Deposition Date: 2020/2/6
Updated in MMDB: 2021/02
Experimental Method:
x-ray diffraction
Resolution: 2.297  Å
Source Organism:
Similar Structures:
Biological Unit for 6Y08: dimeric; determined by author and by software (PISA)
Molecular Components in 6Y08
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
(Gene symbol: Tyms)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
2
2
SulfamethoxazoleSulfamethoxazole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303