6XXJ: Crystal Structure of Human Deoxyhypusine Synthase in complex with spermidine and NAD

PDB ID: 6XXJDownload
MMDB ID: 186531
PDB Deposition Date: 2020/1/27
Updated in MMDB: 2020/04
Experimental Method:
x-ray diffraction
Resolution: 1.41  Å
Source Organism:
Similar Structures:
Biological Unit for 6XXJ: tetrameric; determined by author and by software (PISA)
Molecular Components in 6XXJ
Label Count Molecule
Proteins (4 molecules)
4
Deoxyhypusine Synthase
(Gene symbol: DHPS)
Molecule annotation
Chemicals and Non-standard biopolymers (58 molecules)
1
4
SPERMIDINESPERMIDINE
2
4
NICOTINAMIDE-ADENINE-DINUCLEOTIDENICOTINAMIDE-ADENINE-DINUCLEOTIDE
3
18
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
8
ACETATE IONACETATE ION
5
8
BETA-MERCAPTOETHANOLBETA-MERCAPTOETHANOL
6
10
FORMIC ACIDFORMIC ACID
7
2
(4R)-2-METHYLPENTANE-2,4-DIOL(4R)-2-METHYLPENTANE-2,4-DIOL
8
2
OXAMIC ACIDOXAMIC ACID
9
2
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303