6XVW: Catalytic domain of human PARP-1 in complex with the inhibitor MC2050

PDB ID: 6XVWDownload
MMDB ID: 188520
PDB Deposition Date: 2020/1/22
Updated in MMDB: 2020/06
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 6XVW: monomeric; determined by author
Molecular Components in 6XVW
Label Count Molecule
Protein (1 molecule)
1
Poly [adp-ribose] Polymerase 1
(Gene symbol: PARP1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
5
NICKEL (II) IONNICKEL (II) ION
2
6
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
2-[2-(4-pyridin-2-ylpiperazin-1-yl)ethylsulfanyl]-3~{H}-quinazolin-4-one2-[2-(4-pyridin-2-ylpiperazin-1-yl)ethylsulfanyl]-3~{H}-quinazolin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303