6XLO: Crystal structure of bRaf in complex with inhibitor

PDB ID: 6XLODownload
MMDB ID: 202319
PDB Deposition Date: 2020/6/28
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.493  Å
Source Organism:
Similar Structures:
Biological Unit for 6XLO: dimeric; determined by author and by software (PISA)
Molecular Components in 6XLO
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase B-raf
(Gene symbol: BRAF)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide
2
1
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303