6XI7: Crystal Structure of wild-type KRAS (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF (crystal form I)

PDB ID: 6XI7Download
MMDB ID: 197440
PDB Deposition Date: 2020/6/19
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 6XI7: dimeric; determined by author and by software (PISA)
Molecular Components in 6XI7
Label Count Molecule
Proteins (2 molecules)
1
Isoform 2B of Gtpase Kras
(Gene symbol: KRAS)
Molecule annotation
1
RAF Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: RAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
1
MAGNESIUM IONMAGNESIUM ION
3
2
SULFATE IONSULFATE ION
4
5
CHLORIDE IONCHLORIDE ION
5
3
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303