6XHA: Crystal Structure of KRAS-G12V (GMPPNP-bound) in complex with RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF1/CRAF

PDB ID: 6XHADownload
MMDB ID: 197438
PDB Deposition Date: 2020/6/18
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 2.87  Å
Source Organism:
Similar Structures:
Biological Unit for 6XHA: dimeric; determined by author and by software (PISA)
Molecular Components in 6XHA
Label Count Molecule
Proteins (2 molecules)
1
Isoform 2B of Gtpase Kras
(Gene symbol: KRAS)
Molecule annotation
1
RAF Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: RAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
1
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERPHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
2
4
GLYCEROLGLYCEROL
3
1
MAGNESIUM IONMAGNESIUM ION
4
2
CHLORIDE IONCHLORIDE ION
5
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303