6XG4: X-ray structure of Escherichia coli dihydrofolate reductase L28R mutant in complex with trimethoprim

PDB ID: 6XG4Download
MMDB ID: 200052
PDB Deposition Date: 2020/6/16
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6XG4: monomeric; determined by author
Molecular Components in 6XG4
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
GLYCEROLGLYCEROL
3
1
TRIMETHOPRIMTRIMETHOPRIM
4
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303