6XEB: STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH KETONE INHIBITOR (COMPOUND E)

PDB ID: 6XEBDownload
MMDB ID: 191198
PDB Deposition Date: 2020/6/12
Updated in MMDB: 2020/08
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 6XEB: monomeric; determined by author and by software (PISA)
Molecular Components in 6XEB
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 2
(Gene symbol: HDAC2)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
ZINC IONZINC ION
2
4
SULFATE IONSULFATE ION
3
2
CALCIUM IONCALCIUM ION
4
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
5-{(1S)-7,7-dihydroxy-1-[(1-methylazetidine-3-carbonyl)amino]nonyl}-2-phenyl-1H-imidazole-4-carboxamide5-{(1S)-7,7-dihydroxy-1-[(1-methylazetidine-3-carbonyl)amino]nonyl}-2-phenyl-1H-imidazole-4-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303