6XDM: STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN ARYL KETONE INHIBITOR

PDB ID: 6XDMDownload
MMDB ID: 190660
PDB Deposition Date: 2020/6/11
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 1.56  Å
Source Organism:
Similar Structures:
Biological Unit for 6XDM: monomeric; determined by author and by software (PISA)
Molecular Components in 6XDM
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 2
(Gene symbol: HDAC2)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
ZINC IONZINC ION
2
2
CALCIUM IONCALCIUM ION
3
4
SULFATE IONSULFATE ION
4
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
N-[(1S)-1-[4-(2-fluorophenyl)-1H-imidazol-2-yl]-7,7-dihydroxy-7-(1,2-oxazol-3-yl)heptyl]-1-methylazetidine-3-carboxamideN-[(1S)-1-[4-(2-fluorophenyl)-1H-imidazol-2-yl]-7,7-dihydroxy-7-(1,2-oxazol-3-yl)heptyl]-1-methylazetidine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303