6XDF: Crystal structure of IRE1a in complex with G-4100

PDB ID: 6XDFDownload
MMDB ID: 201105
PDB Deposition Date: 2020/6/10
Updated in MMDB: 2021/04
Experimental Method:
x-ray diffraction
Resolution: 2.54  Å
Source Organism:
Similar Structures:
Biological Unit for 6XDF: dimeric; determined by author
Molecular Components in 6XDF
Label Count Molecule
Proteins (2 molecules)
2
Serine/threonine-protein Kinase/endoribonuclease Ire1
(Gene symbol: ERN1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SODIUM IONSODIUM ION
2
1
4-amino-N-(6-chloro-2-fluoro-3-{[(pyrrolidin-1-yl)sulfonyl]amino}phenyl)quinazoline-8-carboxamide4-amino-N-(6-chloro-2-fluoro-3-{[(pyrrolidin-1-yl)sulfonyl]amino}phenyl)quinazoline-8-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303