6XD3: Structure of the human CAK in complex with THZ1

PDB ID: 6XD3Download
MMDB ID: 192183
PDB Deposition Date: 2020/6/9
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 6XD3: trimeric; determined by author
Molecular Components in 6XD3
Label Count Molecule
Proteins (3 molecules)
1
Cdk-activating Kinase Assembly Factor Mat1
(Gene symbol: MNAT1)
Molecule annotation
1
Cyclin-h
(Gene symbol: CCNH)
Molecule annotation
1
Cyclin-dependent Kinase 7
(Gene symbol: CDK7)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-4-{[4-(dimethylamino)butanoyl]amino}benzamideN-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-4-{[4-(dimethylamino)butanoyl]amino}benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303