6XBL: Structure of human SMO-Gi complex with SAG

PDB ID: 6XBLDownload
MMDB ID: 193458
PDB Deposition Date: 2020/6/6
Updated in MMDB: 2024/11
Experimental Method:
electron microscopy
Resolution: 3.96  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 6XBL: pentameric; determined by author
Molecular Components in 6XBL
Label Count Molecule
Proteins (5 molecules)
1
Smoothened Homolog
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Scfv16
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide
2
1
CHOLESTEROLCHOLESTEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303